TB Testing
ASE offers QuantiFERON (QFT) TB testing through LabCorp. QuantiFERON (QFT) is an interferon-γ release assay (IGRA) that aids in the evaluation of tuberculosis (TB) infections (latent or active)1 and is recommended by the CDC as an alternative to the tuberculin skin test (TST) in certain situations. This modern alternative offers improved performance and quicker results.
- QFT has been shown to be more accurate than the TST in identifying people who may have latent TB infection.
- QFT has been shown to be more reliable than the TST in identifying those who may progress to active TB. QFT is >99% specific, nearly eliminating false-positive readings; and false positive rates for TST have been published as low as 3% in non–BCG-vaccinated populations and as high as 65% when using a 10-mm induration as the cutoff in BCG vaccinated.
- A meta-analysis calculated a pooled sensitivity for TST at 70%, (23 of 25 studies in developed countries) and a pooled sensitivity for QFT at 84% (13 studies in developed countries).